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KMID : 0377819920120101290
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Diagnosis and Treatment
1992 Volume.12 No. 10 p.1290 ~ p.1293
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THYROID STIMULATING ANTIBODIES AND THYROID STIMULATION BLCKING ANTIBODIES DURING THE PREGNANCY AND POSTPARTUM PERIOD
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Abstract
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This report describes a unique pattern of changes in thyroid function and thyroid antibodies in a woman during the course of two pregnancies and two postpartum periods. A 25-year-old woman deveroped hypothyrodism in the postpartum period after the delivery of her first child. She was found to have potent thyroid stimulation blcking antibodies(TSBAb) in theserumj. One year later, she became pregnant again, and during the pregnancy, TSBAb had decreased to an undetectable level. She gave birth to the second healthy child and developed postpartum thyrotoxicosis, probable due to destruction of the thyroid gland, which gradually resolved. In this postpartum period, serum TSBAb levels increased. Eight months postpartum, she developed what appeared to be Graves´ disease with an elevated^(123) 1-thyroid uptake. Serum thyroid-stimulating antibodies (TSAb) were found at that time, and the better understand- the problems so that they can help the patient more properly.
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KEYWORD
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